Glucomannan – Health Information Library (2024)

Uses

Glucomannan is a water-soluble dietary fiber that is derived from konjac root(Amorphophallus konjac). Like other forms of dietary fiber, glucomannanis considered a “bulk-forming laxative.” Glucomannan promotes alarger, bulkier stool that passes through the colon more easily and requiresless pressure—and subsequently less straining—to expel.

Botanical names:

Amorphophallus konjac

What Are Star Ratings?

This supplement has been used in connection with the following health conditions:

Used for Why

3 Stars

Constipation

3 to 4 grams daily in water, followed by a second glass of water

Glucomannan is a water-soluble dietary fiber that has shown to be effective as a bulk-forming laxative.

is a water-soluble dietary fiber that is derived from konjac root. Like other sources of fiber, such as psyllium and fenugreek, glucomannan is considered a bulk-forming laxative. A preliminary trial and several double-blind trials have found glucomannan to be an effective treatment for constipation. The amount of glucomannan shown to be effective as a laxative is 3 to 4 grams per day. In constipated people, glucomannan and other bulk-forming laxatives generally help produce a bowel movement within 12 to 24 hours.

3 Stars

High Cholesterol

3 grams daily

Glucomannan is a viscous, soluble dietary fiber that has been shown to improve metabolism and reduce LDL-cholesterol and non-HDL-cholesterol levels.

is a viscous, soluble dietary fiber that is derived from konjac root. Clinical trials have shown glucomannan has positive impacts on glucose and lipid metabolism. A meta-analysis of 12 randomized controlled trials including 370 participants found that supplementing with 3 grams of glucomannan daily for three weeks or longer reduced LDL-cholesterol levels by 10% and non-HDL-cholesterol levels by 7%.

3 Stars

Metabolic Syndrome

3 to 10 grams daily

Taking a glucomannan fiber supplement may improve metabolic syndrome.

Glucomannan, a type of water-soluble dietary fiber from the root of the konjac plant, may reduce risk factors in people with metabolic syndrome. A double-blind trial found that 8–13 grams per day of glucomannan improved cholesterol levels and blood glucose control in people with metabolic syndrome. It is thought to work in part by acting as a prebiotic fiber, enhancing colonies of beneficial gut bacteria that participate in regulating metabolism. Even in patients with type 2 diabetes, 3 grams of glucomannan per day for four weeks improved blood glucose control and lipid metabolism compared to placebo.

3 Stars

Type 2 Diabetes

1 to 10 grams daily

Glucomannan delays stomach emptying, leading to more gradual glucose absorption and lower blood glucose levels after meals.

Glucomannan is a water-soluble dietary fiber derived from konjac root (Amorphophallus konjac) that delays stomach emptying, leading to a more gradual carbohydrate digestion and glucose absorption. Supplementing with glucomannan before eating has been shown reduce the post-meal elevation of blood glucose levels and long-term supplementation is associated with better blood glucose control and improvements in LDL-cholesterol levels in people with type 2 diabetes. Research in animals suggests glucomannan may be helpful in managing diabetes-related kidney dysfunction. Doses between 1 and 10 grams of glucomannan per day have demonstrated efficacy in clinical research.

2 Stars

Childhood Obesity

2 to 3 grams daily

Glucomannan, a type of fiber, dilutes calories, slows down the eating process, and may make people feel more full despite eating fewer calories.

Increased fiber intake is thought to have potential benefit in a weight-loss program since dietary fiber dilutes calories, slows down the eating process, and may make people feel more full despite eating fewer calories. However, research on using fiber in the treatment of childhood obesity has focused on using fiber supplements rather than comparing low- and high-fiber diets. Supplementation for four months with 2 to 3 grams per day of a bulking agent called , was effective in a group of obese adolescents in one controlled trial, but another controlled trial found no significant effect of 2 grams per day for two months.

2 Stars

Obesity

Adults: 3 to 4 grams daily; adolescents: 2 to 3 grams daily

Supplementing with glucomannan may promote slight weight loss in overweight adults, but findings are mixed.

Glucomannan is a viscous soluble fiber from konjac root that has demonstrated multiple positive effects on metabolic health, including lowering cholesterol, triglyceride, and blood glucose levels. Studies examining its possible role as a weight loss aid, however, have had mixed results. One placebo-controlled trial in 20 participants with obesity found taking 1 gram of glucomannan three times daily at mealtimes for eight weeks, while making no other changes, led to a weight loss of 5.5 pounds. However, an eight-week placebo-controlled trial in 53 adults with overweight and obesity found 1.33 grams of glucomannan three times daily with meals did not impact weight loss. A meta-analysis of findings from eight randomized controlled trials did not find a significant effect of glucomannan on weight loss in people with overweight and obesity.

1 Star

Diverticular Disease

Refer to label instructions

Glucomannan is a water-soluble dietary fiber. One study found that people with diverticular disease had reduced symptoms after taking glucommanan.

is a water-soluble dietary fiber that is derived from konjac root (Amorphophallus konjac). A preliminary clinical trial found that approximately one-third to one half of people with diverticular disease had reduced symptoms of diverticular disease after taking glucommanan. The amount of glucomannan shown to be effective as a laxative is 3–4 grams per day.

1 Star

Hypoglycemia

Refer to label instructions

Glucomannan is a water-soluble dietary fiber. In one trial, adding glucomannan to a meal prevented hypoglycemia in adults with previous stomach surgery.

is a water-soluble dietary fiber that is derived from konjac root (Amorphophallus konjac). In a preliminary trial, addition of either 2.6 or 5.2 grams of glucomannan to a meal prevented hypoglycemia in adults with previous stomach surgery. A trial of glucomannan in children with hypoglycemia due to a condition known as “dumping syndrome” produced inconsistent results.

1 Star

Type 1 Diabetes

Refer to label instructions

Glucomannan delays stomach emptying, leading to more gradual sugar absorption and possibly lowering insulin requirements for people with type 1 diabetes.

Glucomannan is a water-soluble dietary fiber derived from konjac root (Amorphophallus konjac). Glucomannan delays stomach emptying, leading to a more gradual rise in glucose levels after eating carbohydrates. This could result in reduced need for insulin after meals in people with type 1 diabetes. In addition, glucomannan has positive effects on carbohydrate and fat metabolism, as well as the gut microbiota. These properties could lead to benefits in people with type 1 diabetes, but no research has been done to test this possibility.

How It Works

Botanical names:

Amorphophallus konjac

How to Use It

The amount of glucomannan shown to be effective as a laxative is 3–4 grams per day.1, 2 Effective amounts for lowering blood cholesterol have been 4–13 grams per day.3, 4, 5 For controlling blood sugar, 500–700 mg of glucomannan per 100 calories in the diet has been used successfully in controlled research.6, 7 For weight loss, 1 to 3 grams before each meal has been effective.8, 9 When using glucomannan and other dietary fiber supplements, it is best to start out with a small amount and increase gradually. It is recommended to drink at least 8 ounces of water each time any bulk-forming laxative, including glucomannan, is taken.

Where to Find It

Glucomannan is a purified fiber from konjac root that is available as a bulk powder to be taken in hard-gelatin capsules or used as an ingredient in food.

Possible Deficiencies

As glucomannan is not an essential nutrient, no deficiency state exists.

Interactions

Botanical names:

Amorphophallus konjac

Interactions with Supplements, Foods, & Other Compounds

At the time of writing, there were no well-known supplement or food interactions with this supplement.

Interactions with Medicines

As of the last update, we found no reported interactions between this supplement and medicines. It is possible that unknown interactions exist. If you take medication, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a supplement with your doctor or pharmacist.

Side Effects

Botanical names:

Amorphophallus konjac

Side Effects

People with any disorder of the esophagus (the tube leading from the mouth to the stomach) should not take any fiber supplement in a pill form, as the supplement may expand in the esophagus and lead to obstruction.10 Preliminary reports in humans, as well and animal research, suggest that some people may be sensitive to inhaled glucomannan powder.11

Since intestinal bacteria ferment water-soluble fibers, a great deal of intestinal gas may be produced in individuals not accustomed to a high fiber diet, leading to flatulence and abdominal discomfort.

Related Information

Glucomannan – Health Information Library (1)

References

1. Marsicano LJ, Berrizbeitia ML, Mondelo A. Use of glucomannan dietary fiber in changes in intestinal habit. G E N 1995;49:7-14 [in Spanish].

2. Passaretti S, Franzoni M, Comin U, et al. Action of glucomannans on complaints in patients affected with chronic constipation: a multicentric clinical evaluation. Ital J Gastroenterol 1991;23:421-5.

3. Arvill A, Bodin L. Effect of short-term ingestion of konjac glucomannan on serum cholesterol in healthy men. Am J Clin Nutr 1995;61:585-9.

4. Vuksan V, Jenkins DJ, Spadafora P, et al. Konjac-mannan (glucomannan) improves glycemia and other associated risk factors for coronary heart disease in type 2 diabetes. A randomized controlled metabolic trial. Diabetes Care 1999;22:913-9.

5. Vuksan V, Sievenpiper JL, Owen R, et al. Beneficial effects of viscous dietary fiber from Konjac-mannan in subjects with the insulin resistance syndrome: results of a controlled metabolic trial. Diabetes Care 2000;23:9-14.

6. Vuksan V, Jenkins DJ, Spadafora P, et al. Konjac-mannan (glucomannan) improves glycemia and other associated risk factors for coronary heart disease in type 2 diabetes. A randomized controlled metabolic trial. Diabetes Care 1999;22:913-9.

7. Vuksan V, Sievenpiper JL, Owen R, et al. Beneficial effects of viscous dietary fiber from Konjac-mannan in subjects with the insulin resistance syndrome: results of a controlled metabolic trial. Diabetes Care 2000;23:9-14.

8. Walsh DE, Yaghoubian V, Behforooz A. Effect of glucomannan on obese patients: a clinical study. Int J Obes 1984;8:289-93.

9. Vita PM, Restelli A, Caspani P, Klinger R. Chronic use of glucomannan in the dietary treatment of severe obesity. Minerva Med 1992;83:135-9 [in Italian].

10. Henry DA, Mitchell AS, Aylward J, et al. Glucomannan and risk of oesophageal obstruction. Br Med J 1986;292:591-2.

11. Werley MS, Burleigh-Flayer H, Mount EA, Kotkoskie LA. Respiratory sensitization to konjac flour in guinea pigs. Toxicology 1997;124:115-24.

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How It Works »

Last Review: 05-24-2015

Glucomannan – Health Information Library (2)

Copyright © 2024 TraceGains, Inc. All rights reserved.

Learn more about TraceGains, the company.

The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.

Topic Contents

  • Uses
  • How It Works
  • Interactions
  • Side Effects
  • Related Information
  • References

PeaceHealth endeavors to provide comprehensive health care information, however some topics in this database describe services and procedures not offered by our providers or within our facilities because they do not comply with, nor are they condoned by, the ethics policies of our organization.

Health Information Library

Glucomannan – Health Information Library (3) Glucomannan – Health Information Library (4)

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Glucomannan – Health Information Library (2024)

FAQs

Has anyone lost weight with glucomannan? ›

As you can see, weight loss was significantly greater among those who supplemented with glucomannan. Several other studies agree with these results. Glucomannan caused modest weight loss in overweight and obese individuals when regularly ingested before a meal ( 9 , 10 , 11 ).

What should you not take with glucomannan? ›

People who use hypoglycemic drugs, insulin or any other medication should always consult a doctor before using glucomannan, as this supplement can alter the effect of some medications.

What foods are high in glucomannan? ›

Glucomannan is found in shirataki noodles, which are made from konjac root. Shirataki noodles are a good stand-in for regular noodles or pasta in reduced calorie or low-carb diets. There is no set time when you should take glucomannan.

Is glucomannan safe long term? ›

Glucomannan powder and capsules are possibly safe when taken with plenty of water for up to 4 months. But taking glucomannan products without water, especially as tablets, is possibly unsafe.

Why is glucomannan banned? ›

Glucomannan expands rapidly after absorbing water, and intake of an excess amount of glucomannan can lead to discomfort and prevents absorption of nutrients, leading to malnutrition. Moreover, it interferes with the absorption of medications and may worsen symptoms or illness.

What is the number 1 prescribed weight loss? ›

Phentermine is the oldest and most widely used weight loss medication. It was originally used as a short-term medication to jump-start weight loss, but now newer medical guidelines have added it to long-term therapy. Some patients may lose about 5% of their body weight by taking phentermine.

Is glucomannan bad for the kidneys? ›

Conclusions. The disturbance of lipid, glucose, and amino acid metabolism is closely associated with the advancement of diabetic kidney disease, and glucomannan treatment could be efficient in the management of diabetic kidney disease.

Can glucomannan cause high blood pressure? ›

Some early research suggests that glucomannan might improve blood pressure in people with high blood pressure.

Can you take glucomannan on an empty stomach? ›

Supplementing with glucomannan before eating has been shown reduce the post-meal elevation of blood glucose levels and long-term supplementation is associated with better blood glucose control and improvements in LDL-cholesterol levels in people with type 2 diabetes.

What are the side effects of now glucomannan? ›

Adverse Reactions

The hypoglycemic effects are potentially dangerous to patients with diabetes. Glucomannan has been linked in case reports to cholestatic hepatitis and occupational asthma. Minor adverse effects are normally GI related and include diarrhea, flatulence, abdominal discomfort, and bloating.

What is the safest way to take glucomannan? ›

Take glucomannan with at least 8 ounces of water. Many studies suggest taking it before meals to help increase feelings of fullness. Start slowly and increase gradually to prevent gastrointestinal side effects. If you are taking any medications, discuss the timing of supplementation with your healthcare provider.

Is glucomannan anti-inflammatory? ›

All these findings speak in favor of the anti-inflammatory activity of glucomannan.

Who should not take glucomannan? ›

Glucomannan has not been proved safe for the following people:
  • Pregnant or breastfeeding women.
  • Children.
  • If you are diabetic, speak to your doctor before taking glucomannan as it can reduce the absorption of some diabetes medications.
Nov 22, 2022

Is glucomannan the same as psyllium? ›

The main difference between glucomannan and psyllium is their source. Glucomannan is derived from the root of the konjac plant, whereas psyllium husks are taken from the Plantago ovate shrub. As they are both sources of soluble fibre, glucomannan and psyllium husks have a range of common characteristics.

Can glucomannan cause bowel obstruction? ›

Supplements containing glucomannans pose a risk for choking and bowel obstruction if they are not taken with sufficient water. Other adverse effects include diarrhea, belching, and bloating; in one study people taking glucomannans had higher triglyceride levels.

Does glucomannan speed up metabolism? ›

What you need to know. For all intents and purposes, modern Glucomannan is as effective as any other dietary fiber for nutritional purposes. Glucomannan and fiber help control weight in three ways: reducing appetite; managing blood-sugar; and increasing fat metabolism.

Is glucomannan similar to Ozempic? ›

Konjac, rich in a soluble fiber called glucomannan, is known for its ability to regulate blood sugar levels and support weight management, presenting it as a natural alternative to Ozempic for some individuals.

Has anyone lost weight using Metamucil? ›

One study found that participants who consumed Metamucil had a higher rate of weight loss compared to those who didn't. Another study suggested that adding fiber to one's diet, like Metamucil, could potentially lead to weight loss when combined with a calorie-restricted diet.

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