What is the window period for an HIV test? | Guides (2024)

Guides

What is the window period?

The window period is time between HIV infection and the point when a test will give an accurate result for a certain percentage of samples.

Different types of tests have different window periods.

  • 4th generation antibody/antigen (Ab/Ag) tests: 45 days to detect 99% of samples.
  • 3rd generation antibody only tests: 60 daysto detect 99% of samples.
  • Point of care tests (self-sampling, self-testing and rapid tests: 90 days to detect 99% of samples.

During the window period, someone can be very infectious but still test HIV negative.

UK guidelinesrecommend a window period of six weeks for a 4th generation antigen/antibody test (BHIVA/BASHH 2020).

By this time 99% of infections will be detected (see Figure 7). Testing after only four weeks will detect 95% of infections.

A negative result at 6 weeks with a 4th generation test does not need to be confirmed.

A negative result from testing earlier, for example after four weeks, does need to be confirmed by a second later test.

Figure 7: Time to develop antibodies *

95% people by week 4, 99% by week 6 and more than 99.9% by week 12
What is the window period for an HIV test? | Guides (1)

Figure 7 above shows the range of times that people can take to respond to HIV infection.

The earliest marker is HIV viral load. This is in the first weeks after infection (usually from 1 to 6 weeks after exposure). A high viral load is related to seroconversion symptoms.

The first HIV protein (antigen) that can be measured is p24 (from 1 to 8 weeks after exposure).

Viral load and p24 tests are not accurate for diagnosing early HIV if the results are negative.

An HIV antibody response can be detected as early as two weeks in a few people and in more than 99.9% of people by 12 weeks. An antibody test at 4 weeks will detect 95% of infections.

Antibody testing at 4 weeks can give you a good indication of your HIV status, but you need a test at 12 weeks after the exposure to be considered HIV negative.

Figure 8: Timeline for HIV infection, immune responses and window period for tests *

What is the window period for an HIV test? | Guides (2)

* Both these graphics need to be updated to also show the six week time point.

Last updated: 1 May 2023.

What is the window period for an HIV test? | Guides (2024)

FAQs

What is the window period for an HIV test? | Guides? ›

The window period depends on the type of HIV test. Antibody tests can usually detect HIV 23 to 90 days after exposure. Most rapid tests and self-tests are antibody tests. A rapid antigen/antibody test done with blood from a finger stick can usually detect HIV 18 to 90 days after exposure.

Who guidelines for HIV testing window period? ›

In most cases, people develop antibodies to HIV within 28 days of infection. During this time, people are in the so-called “window period” when they have low levels of antibodies which cannot be detected by many rapid tests, but they may still transmit HIV to others.

What is the conclusive window period for HIV test? ›

The window period of modern laboratory HIV tests is 45 days. The window period of rapid, point-of-care tests and self-tests is 90 days.

What is the window period for instant HIV test? ›

National testing guidelines set out a 90-day window for HIV self tests. Blood tests that you send off to a lab and those available at sexual health clinics have a testing window of 45 days.

Is the 6 month HIV window period outdated? ›

Testing at 3 and 6 months after possible exposure will detect almost all HIV infections. However, there are no guarantees as to when an individual will produce enough antibodies to be detected by an HIV test. If you have any unexplained symptoms, talk with your healthcare provider and consider re-testing for HIV.

What is the CDC guidelines for HIV window period? ›

The window period depends on the type of HIV test. Antibody tests can usually detect HIV 23 to 90 days after exposure. Most rapid tests and self-tests are antibody tests. A rapid antigen/antibody test done with blood from a finger stick can usually detect HIV 18 to 90 days after exposure.

What are the new CDC guidelines for HIV testing? ›

CDC recommends all patients between the ages of 13 and 64 get tested for HIV at least once as part of routine health care. Screen patients who may have ongoing risk factors for HIV at least annually. Use “opt-out” approach to remove stigma associated with HIV testing and foster earlier diagnosis and treatment.

Which HIV test has the shortest window period? ›

A nucleic acid (NAT) test has the shortest window period. It can tell if you have an HIV infection from 10 to 33 days after exposure.

What is the period for HIV positive test? ›

Antigen/Antibody Test—An antigen/antibody test performed by a laboratory on blood from your vein can usually detect HIV infection 18 to 45 days after exposure. An antigen/antibody test done with blood from a finger prick takes longer to detect HIV (18 to 90 days after an exposure).

How soon to retest for HIV? ›

Received an HIV-negative test result on a baseline HIV test for an incident of possible HIV exposure in the past 72 hours; in this case, and if PEP has not been initiated, re-test at 4 weeks after exposure, and if the results are still negative or discordant, the person should be re-tested again at 12 weeks after ...

What are the 7 warning signs of HIV? ›

Primary infection, also called acute HIV
  • Fever.
  • Headache.
  • Muscle aches and joint pain.
  • Rash.
  • Sore throat and painful mouth sores.
  • Swollen lymph glands, also called nodes, mainly on the neck.
  • Diarrhea.
  • Weight loss.
Feb 9, 2024

How long does it take for HIV to show up? ›

Most people infected with HIV experience a short, flu-like illness that occurs 2-6 weeks after infection. After this, HIV may not cause any symptoms for several years. It's estimated up to 80% of people who are infected with HIV experience this flu-like illness.

Can HIV be cured within 72 hours of infection? ›

Emergency HIV drugs

PEP must be started within 72 hours of coming into contact with the virus for it to be effective. It's only recommended following higher risk exposure, particularly where the sexual partner is known to be positive. PEP involves taking HIV treatment every day for 1 month.

Is the 6 month HIV window conclusive? ›

If you know exactly when you may have come into contact with the virus, take a test 3 months after that date. Tests 3 months after exposure should be 99% accurate. If you are having symptoms of HIV, see your doctor right away. Your doctor may want to use a test that can look for the virus directly in your body.

Is it better to test for HIV 3 months or 6 months? ›

Patients with risk factors for contracting HIV should be tested as frequently as every 3 to 6 months. The fourth-generation HIV test is the recommended test and can detect HIV as early as 14 days following transmission by detecting HIV p24 Ag.

What is the longest HIV survivor without treatment? ›

A woman in Barcelona has maintained an undetectable HIV viral load for more than 15 years after stopping antiretroviral therapy, according to a case report presented on Friday at the 24th International AIDS Conference (AIDS 2022) in Montreal.

WHO guidelines for HIV self-testing? ›

In 2016, WHO published the first global guidelines on HIV self-testing, in which HIV self-testing was recommended to be offered as an additional approach to HIV testing services. WHO also coordinates the HIV self-testing research and policy hub which monitors the use of HIV self-tests around the world.

How long must you wait to test for HIV? ›

Antigen/Antibody Test—An antigen/antibody test performed by a laboratory on blood from your vein can usually detect HIV infection 18 to 45 days after exposure. An antigen/antibody test done with blood from a finger prick takes longer to detect HIV (18 to 90 days after an exposure).

What is the window period for 4th gen HIV lab test? ›

The fourth-generation HIV test is the recommended test and can detect HIV as early as 14 days following transmission by detecting HIV p24 Ag. HIV RNA viral load can be performed if an acute infection is suspected (less than 2 weeks after possible exposure to HIV).

Is an HIV test after 3 weeks accurate? ›

For most types of HIV tests, you'll need to wait 2 weeks or more after exposure to get an accurate result. You can infect others soon after you're exposed, so practice safe sex and take other precautions in the meantime. Almost everyone who is HIV-positive has detectable levels of antibodies at 3 months.

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